Look — I'm not gonna say it's wrong, but you've got a bit of a reverb overload going on there. Running both the BigSky and the RV-6 after the Afterneath feels like bringing a whole orchestra to a solo gig; maybe try cutting one of the reverbs out to let that Jazzmaster's natural tone shine through. And while the Big Muff is a classic, consider placing it after your reverbs to see if that fuzz can cut through the mix better.